Read full bio


Undergraduate Education: BS, Microbiolology, University of Oklahoma, 1997

Medical School: MD, Baylor College of Medicine, 2008

Post Graduate Education: PhD, Baylor College of Medicine, 2006

Internship: Transitional year, The Methodist Hospital, 2009

Residency: Ophthalmology, Duke University, 2012

Fellowships: Medical Retina, Duke University, 2013

                  Uveitis, University of Washington, 2014 

Board Certification: American Board of Ophthalmology,2013

Memberships: American Academy of Ophthalmology (AAO)    

                    Association for Research in Vision and Ophthalmology (ARVO)

Download CV

Clinical Interests

Dr. Pepple specializes in uveitis, including iritis, pars planitis, retinitis, choroiditis and scleritis, and medical retinal disease including age related macular degeneration, diabetic retinopathy, and retinal vascular diseases.

Research & Focus

Dr. Pepple’s laboratory is interested in understanding the pathogenesis of ocular inflammation, and developing new therapies to treat patients with uveitis. Her lab is also interested in novel applications of advanced imaging modalities such as optical coherence tomography (OCT) and IVIS in clinical and pre-clinical studies of uveitis.

Awards & Honors

2014 NEI K08 award

2013 Heed Ophthalmic Foundation fellowship award

2012 Edward K. Isbey Jr., M.D. Resident Award for Excellence in Clinical Care, Ethics, and Research

2007 Milton Finegold Graduate Student Achievement Award

2001 John J. Trentin Scholarship Award for Academic Excellence



Gutowski MB, Wilson L, Van Gelder RN, Pepple KL. In Vivo Bioluminescence Imaging for Longitudinal Monitoring of Inflammation in Animal Models of Uveitis. Invest Ophthalmol Vis Sci. 2017 Mar 1;58(3): 1521-1528. PubMed PMID: 28278321

Kim AY, Rodger DC, Shahidzadeh A, Chu Z, Koulisis N, Burkemper B, Jiang X, Pepple KL, Wang RK, Puliafito CA, Rao NA, Kashani AH. Quantifying retinal microvascular changes in uveitis using spectral domain optical coherence tomography angiography (SD-OCTA). AM J Ophthalmol. 2016 Sep 1. PMID 27594138

Pepple KL, Choi WJ, Wilson L, Van Gelder RN, Wang RK. Quantitative assessment of anterior segment inflammation in a rat model of uveitis using spectral domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2016 Jul 1;57(8):3567-75. PMID 27388049

Zhang Q, Lee CS, Chao J, Chen CL, Zhang T, Sharma U, Zhang A, Liu J, Rezaei K, Pepple KL, Munsen R, Kinyoun J, Johnstone M, Van Gelder RN, Wang RK. Wide-field optical coherence tomography based microangiography for retinal imaging. Sci Rep. 2016 Feb 25;6:22017. PMID: 26912261

Pepple KL, Rotkis L, Van Grol J, Wilson L, Sandt A, Lam DL, Carlson E, Van Gelder RN. (2015) Primed Mycobacterial Uveitis (PMU): Histologic and Cytokine Characterization of a Model of Uveitis in Rats. Invest Ophthalmol Vis Sci. Dec 1:56(13):8438-48. doi: 10.1167/iovs.15-17523. PubMed PMID: 26747775

Pepple KL, Rotkis L, Wilson L, Sandt A, Van Gelder RN. (2015) Comparative Proteomic Analysis of Two Uveitis Models in Lewis Rats. Invest Ophthalmol Vis Sci. Dec 1:56(13):8449-56. doi: 10.1167/iovs.15-17524. PubMed PMID: 26747776




Primary Clinical Office

UW Medicine Eye Institute

Harborview Medical Center
908 Jefferson St., 7th Floor
Seattle, WA
Clinic Phone: 206-744-2020
Clinic Fax: 206-897-4320

Mailing Address:
Box 359608
325 Ninth Ave.
Seattle, WA 98104
Academic Phone: 206-543-7250

Additional Offices

UW Medicine – Vision Science Center

South Lake Union

Box 355058

750 Republican St., Bldg. E
Seattle, WA 98108
Phone: 206-543-7250
Fax: 206-685-9315

Mailing Address:
Vision Science Center

Box 358058
750 Republican St., Bldg. E
Seattle, WA 98108






UW Medicine – Vision Science Center

South Lake Union